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Cytogenetic Profile of a Thymoma
A Case Report and Review of the Literature
Cytogenetic analysis of mixed lymphocyte and epithelial
thymoma in a nonmyasthenic female patient revealed deletion of part of the short arm of chromosome 6. To our
knowledge, this cytogenetic abnormality in a benign thymoma has not been previously described in the literature,
which is reviewed.
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Clinical and immunohistochemical study of eight cases with thymic carcinoma
Conclusions: In this small series, it is suggested that a complete resection suggests a favorable
result. Immunohistochemical results reveal that the expression of these proteins might indicate the
aggressiveness of thymic carcinoma.
Background
Thymic carcinoma is a rare type of malignant tumor [1,2].
It is more invasive and with a poorer prognosis than Thymoma.Read More →

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A cytologic diagnosis of thymoma is extremely challenging. In part, this is because the tumor is uncommon and aspirates are infrequently encountered, a technically proficient interventional radiolo- gist is needed, epithelial cells may be difficult to recognize in lymphoid rich aspirate smears, and there is inherent sampling error in a tumor that frequently displays heterogeneous histopathology. Critical to the cytologic diagnosis of most WHO Type B thymomas is the recognition of a distinct population of epithelial cells mixed with lymphocytes.Read More →